Description
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com
Job Function:
Discovery & Pre-Clinical/Clinical DevelopmentJob Sub Function:
Pharmaceutical Product R&DJob Category:
People LeaderAll Job Posting Locations:
Beerse, Antwerp, BelgiumJob Description:
At Johnson & Johnson Innovative Medicine (JJIM) we strive to improve life and outcomes of millions of patients worldwide. Do you want to be a true pioneer and join us in our journey towards the development of innovative therapeutics delivered orally? If so, this Scientific Director role could be an exciting opportunity to explore!
About the Department
The Global Pharmaceutical Product Development and Supply organization (PPDS) is within the Discovery, Product Development and Supply (DPDS) organization of Pharmaceutical Companies of Johnson and Johnson responsible for the development of Pharmaceutical Dosage Forms with development centers located in the US, Asia, and Europe.
Oral Solids Development (OSD) consists of 45+ dedicated and enthusiastic colleagues from ten different nationalities. Within OSD, scientists are formulating both small molecules, as well as novel oral modalities for advanced drug delivery into dosage forms for oral, intravesical, inhalation, and other drug administration routes.
For the location in Beerse, Antwerp, Belgium there is a vacancy for a Senior Scientific Msanager / Scientific Manager Oral Solids Development (OSD).
The overall mission of the role is to lead and guide the formulation and process development for the solid dosage forms of the oral peptide portfolio of JJIM. Key elements of the role are strong networking within global teams, strengthening and assuring the scientific knowledge/expertise within oral solids development, innovation, customer focus and teamwork, and ensuring formulation strategies and processes which align with JJIM commercial capabilities, with a specific focus on the formulation development of small peptides into oral solid dosage forms.
Your Impact:
As a valued member of our Oral Solids Development team, you'll play a crucial role in shaping the future of drug formulation and process development of oral peptides. Your responsibilities will encompass a diverse range of activities:
- Leading the formulation development of small peptides into oral solid dosage forms, both internally and through strategic partnerships.
- Cultivating strong relationships with cross-functional stakeholders, fostering collaboration with departments spanning Discovery Pharmaceutics, Preclinical and Clinical, Biopharmaceutical Sciences, Analytical Development, API Development, Clinical Supply Chain, Regulatory, and more.
- Pioneering innovation by building upon existing Formulation and Technology Platforms, harnessing your expertise to create novel therapeutic solutions.
- Leading a team of scientists focusing on oral peptide delivery and developing talent within the department. Identify opportunities for growth of the team members and building personal development plans.
- Collaborating closely with fellow OSD scientists to design, plan, and execute formulation development activities across our product portfolio.
- Meticulously documenting scientific data and progress, contributing to regulatory submissions, scientific papers, intellectual property and strategic decisions.
- Ensuring compliance with regulatory standards, GMP, and performance-based occupational exposure levels.
What We Seek:
We're seeking a dynamic individual with a proven track record in drug product formulation development of oral small peptides. Your qualifications and attributes include:
- A Ph.D. in Pharmaceutical Sciences, Industrial Pharmacy, Biochemical Engineering, Chemical Engineering, Biological or Physical Sciences, or Equivalent with at least 5 to 10 years of relevant industry and/or academic experience. Alternatively, a Bachelor or Master's Degree in relevant areas accompanied by at least 15 years of relevant experience.
- Expertise spanning formulation selection and process development (including technologies such as direct compression, granulation, and film coating) for small peptides into oral solid dosage forms is an absolute must.
- Familiarity with pre-formulation activities and physico-chemical characterization of APIs and final drug products.
- Experience with targeted and/or local delivery of oral formulations is a distinctive advantage as well as a deep understanding of in vitro- and biopharmaceutical testing and performance of oral small peptides.
- Proven expertise in implementing cutting-edge technologies, determining critical quality attributes, process parameters, and material attributes.
- A readiness to engage in international travel (approximately 5-15% of the time).
Why JJIM:
Our offer:
- An exciting position in an international and dynamic environment with continuous learning and growth opportunities
- Working on a site that harbors all aspects of the drug discovery and development process, located close to the vibrant city of Antwerp.
- A competitive salary, on-site sport accommodations, health/energy programs and other benefits for you and your family.
- An inclusive team environment where diversity and different opinions are respected and valued, and the importance of a good work-life balance is recognized.
