Director of Information Systems

Are you ready to shape the future of IT in a fast-paced, global organization?

We are seeking a visionary Director of Information Systems (IS) to lead our digital transformation efforts. This role will be responsible for shaping and executing a comprehensive strategy for our global IT systems, driving data excellence, and evolving our business applications to support innovation, growth, and operational efficiency.

This is more than an IT role — it's a strategic leadership opportunity at the heart of our business, combining high-level strategy with hands-on execution and team leadership.

Why this role matters

As Director of IS, you will be a key player in defining and delivering our global information strategy. You will lead large-scale IT initiatives, drive digital innovation, and ensure best-in-class system performance, security, and compliance. You will work cross-functionally to align technology with business goals and help unlock the full potential of data across the company.

You will report to senior leadership and act as a trusted advisor on all matters related to information systems, business applications, IT security, digital solutions, and enterprise technology.

Key Responsibilities

Strategic Leadership

• Define and implement a forward-looking IS strategy aligned with business priorities.
• Identify and integrate emerging technologies to drive innovation and competitive edge.
• Lead major IT and digital transformation projects across departments globally.
• Collaborate with senior leaders to ensure technology empowers business strategy.

Operational & Infrastructure Management

• Oversee IT operations, systems infrastructure, cybersecurity, and support services.
• Ensure scalability, reliability, and cost-efficiency of IT systems.
• Lead major systems upgrades and migrations, ensuring seamless business continuity.

Business Applications & Data Excellence

• Define and execute the roadmap for the evolution of core business applications.
• Oversee the integration and optimization of enterprise systems to enhance user experience and operational efficiency.
• Champion data governance, quality, and accessibility to support informed decision-making.
• Ensure alignment of business applications with organizational priorities and compliance requirements.

Team Leadership & Culture

• Build and inspire a high-performing IT team with a focus on accountability, growth, and innovation.
• Create a culture of excellence, collaboration, and continuous improvement.
• Foster knowledge sharing and integration across business units.

Data Governance, Security & Compliance

• Ensure compliance with regulatory standards (e.g., GDPR, HIPAA, SOX).
• Develop security policies, manage risk, and respond proactively to cyber threats.
• Establish robust disaster recovery and business continuity plans.

Financial & Vendor Management

• Own and optimize the IS budget, ensuring ROI from investments.
• Negotiate vendor contracts and oversee service provider performance.
• Balance cost control with strategic value delivery.

Stakeholder Engagement

• Serve as a key partner to executives, delivering insights that guide digital transformation.
• Promote IS as a business enabler and drive adoption of new technologies.
• Strengthen internal and external partnerships to support IT initiatives.

About You

We are looking for a transformative leader with the following background:

Education & Experience

• Bachelors in IT, Computer Science, or related field (advanced degree preferred).
• 10+ years in IT, with 5+ years in a senior leadership role.
• Experience managing global IT operations in a complex, multinational environment.
• Strong technical foundation across infrastructure, applications, and cybersecurity.
• Track record of successfully leading high-impact projects and change initiatives.

Leadership & Soft Skills

• Visionary, pragmatic, and results driven.
• Outstanding communicator and influencer across technical and non-technical audiences.
• Skilled in managing cross-functional teams and building strong partnerships.
• Experience in biotech/pharma or regulated industries is a strong plus.

Location & Flexibility

This global leadership role can be based in Mechelen, Belgium or Chicago, United States. Occasional international travel as needed.

Ready to make an impact?

Apply now to help shape the future of our global information system.

Location & Flexibility

This global leadership role can be based in Mechelen, Belgium or Chicago, United States. Occasional international travel as needed.

Ready to make an impact?

Apply now to help shape the future of our global information system.